What Is THCp?

THCp (tetrahydrocannabiphorol) is a naturally occurring phytocannabinoid found in the cannabis plant, more specifically in cannabis sativa. As one of the most intriguing newly discovered cannabinoids, THCp has quickly drawn attention due to its unusually high potency and distinctive chemical structure.

First isolated by a team of Italian researchers in 2019, this compound has since become a subject of great interest in cannabis science. While THCp is a naturally occurring cannabinoid, it is only present in very low concentrations in most cannabis plants, making it less common than well-known compounds like tetrahydrocannabinolic acid (THCa) or cannabidiol (CBD).

Still, the discovery of THCp adds a new dimension to the growing variety of hemp derived cannabinoids—each offering unique effects and potential benefits.

Chemical Structure and Potency

The most notable feature of THCp is its extended alkyl side chain. Unlike traditional THC, which has a five-carbon chain, THCp has a seven-carbon chain. This small yet critical difference greatly enhances its binding to CB1 receptors, the part of the endocannabinoid system responsible for regulating mood, pain, and other central functions.

Because THCp binds so strongly to these receptors, studies suggest it may be significantly more potent than regular THC the compound responsible for cannabis’s intoxicating effects. In fact, some research indicates that THCp may exhibit in vivo cannabimimetic activity higher than THC—making it a cannabinoid of particular interest for both therapeutic and recreational use.

How THCp Works in the Body

Like other cannabinoids, THCp interacts with the human endocannabinoid system, specifically by targeting the CB1 receptors in the brain and central nervous system. What sets it apart is that THCp binds more effectively to these receptors, possibly intensifying its psychoactive effects beyond what users typically experience with traditional THC.

The result? Stronger and longer-lasting effects, even at lower doses—a trait that has stirred plenty of curiosity in the cannabis community and among researchers.

Potential Benefits of THCp

While research is still emerging, researchers found early evidence that THCp may provide a variety of benefits. These may include:

• Pain relief to patients dealing with chronic or neuropathic pain
• Possible mood-stabilizing effects
• Appetite stimulation and anti-nausea support

Because THCp binds to CB1 receptors more strongly than THC, the compound may be effective in smaller doses, making it an efficient option for certain therapeutic needs. However, as with all hemp derived cannabinoids, more data is needed to fully understand its medicinal potential.

THCp vs. THC: What’s the Difference?

Though both THC and THCp share similar origins and effects, their chemical structure sets them apart. As mentioned, THCp has a seven-carbon chain (compared to THC’s five), which allows it to bind with greater affinity to cannabinoid receptors.

This stronger binding translates to more intense psychoactive effects, giving THCp a distinct identity in the cannabis world—despite being present in very low concentrations.

Ways to Consume THCp

THCp can be consumed in many of the same ways as other cannabinoids:

• Vapes: Quick onset, strong effects
• Edibles: Longer-lasting, more gradual experience
• Tinctures: Controlled dosing, sublingual delivery
• Topicals: Localized relief without intoxication

Because of its potency, first-time users should start low and go slow, especially if they’re unfamiliar with newly discovered cannabinoids like THCp.

Side Effects and Safety

Though THCp is a naturally occurring cannabinoid, its intensity means it should be approached with care. Potential risks and side effects include:

• Anxiety or paranoia
• Dizziness or fatigue
• Dry mouth and increased heart rate

Because THCp binds more tightly to receptors, users may feel overwhelmed if they consume too much too quickly. Always begin with small doses and consider how it might interact with your body—especially if you're already using medical marijuana or other cannabis products.

THCp’s Legal Status

Is THCp legal? That depends.

Under the 2018 Farm Bill, hemp derived cannabinoids like THCp are federally legal if they are extracted from hemp and the final product contains less than 0.3% Delta 9 THC. However, state laws vary, and some states may restrict THCp because of its strong psychoactive effects.

As always, check your local laws before purchasing or using this newly discovered cannabinoid.

Will THCp Show Up on a Drug Test?

Even though most drug tests don’t specifically screen for THCp, it may still trigger a positive result. Because THCp binds to CB1 receptors and shares a similar metabolic pathway with THC, it’s likely that THCp may show up on a drug test as THC.

If you’re subject to testing or hold a medical marijuana card, use caution when consuming THCp products.

Research and the Future of THCp

Since being identified by a team of Italian researchers, THCp has sparked a wave of curiosity and study. Early indications show that THCp may exhibit in vivo cannabimimetic activity higher than THC, suggesting exciting therapeutic possibilities.

As research progresses, we may discover more about cannabinoids found in cannabis sativa L, including others that are potentially awaiting discovery. For now, THCp remains a fascinating glimpse into the future of cannabinoid science.

Final Thoughts

THCp is one of the most promising newly discovered cannabinoids in recent cannabis research. Found in very low concentrations in the cannabis plant, this naturally occurring phytocannabinoid binds powerfully to cannabinoid receptors, producing strong psychoactive effects—even in small doses.

While THCp is a naturally occurring cannabinoid, users should remain aware of its risks and side effects, its potential to appear on drug tests, and the evolving laws regarding its use. Whether you're a cannabis connoisseur or a curious patient, THCp is worth watching as science catches up to its powerful potential.